Some studies about COVID-19 and pregnant people are going on right now and data may be available soon. From the data we do have, there has not been an effect from the vaccine on pregnancy or pregnancy outcomes. There were vaccine study volunteers who were vaccinated and then learned they were pregnant. The manufacturer will follow these people throughout the pregnancy and birth. In the meantime, the American Board of Obstetrics and Gynecology has said that they support pregnant people getting the COVID-19 vaccine if they meet the ACIP recommendations for getting COVID-19 vaccine. We know that pregnant people are at a higher risk of severe disease compared to non-pregnant people. A pregnant person who is part of a group recommended/prioritized to receive a COVID-19 vaccine may choose to be vaccinated.
mRNA vaccines are not thought to be a risk to the breastfeeding infant. A person who is breastfeeding who is part of a group recommended to receive a COVID-19 vaccine (e.g., health care workers) may choose to be vaccinated.
Immunocompromised means a person has a weak immune system. People with HIV infection, other immunocompromising conditions, or who take medications or therapies that weaken the immune system might be at increased risk for severe COVID-19. We currently do not have data on vaccine safety and efficacy in these groups. People with a weak immune system who want to receive COVID-19 vaccine should be informed that there is little information about how effective or how safe the vaccine is. These people may not have a strong immune response to the vaccine (they may have less protection), so they should continue to follow guidance to protect themselves from COVID-19.