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Mammogram screening following COVID-19 vaccination

Patients may have questions regarding COVID-19 vaccination and when it is okay to have a mammogram. Regardless of vaccination status, people should contact their health care provider right away if they have breast symptoms (e.g., breast pain, lump, or other changes).

Use these talking points if you receive questions:

  • If you were recently vaccinated for COVID-19 and are due for a mammogram, ask your doctor if you should wait to get your mammogram.

  • People who have received a COVID-19 vaccine can have swelling in the lymph nodes (lymphadenopathy) in the underarm near where they got the shot.

    • This swelling is a normal sign that your body is building protection against COVID-19. However, it is possible that this swelling could cause a false reading on a mammogram.

  • Some experts recommend getting your mammogram before being vaccinated with COVID-19 vaccine or waiting to get your mammogram until four to six weeks after getting your final dose of vaccine (i.e., four to six weeks after the second dose of a two-dose vaccine or four to six weeks after a one-dose vaccine).


Should I reschedule my mammogram if I recently received the COVID-19 vaccine?

Not necessarily. There's concern that side effects from the vaccine to prevent coronavirus disease 2019 (COVID-19) could be mistaken for breast cancer on a mammogram. But that doesn't mean you should cancel your mammogram if you've received your vaccine. Instead, contact the facility where your mammogram is scheduled to ask for guidance.

The vaccine that prevents COVID-19 can cause swollen lymph nodes under the arm in which the shot was given. Your lymph nodes are part of your body's germ-fighting immune system. The swelling in the lymph nodes is a sign that your body is responding to the vaccine and building up defenses against the virus that causes COVID-19.

Breast cancer also can cause swelling in the armpit if cancer cells spread to the lymph nodes.

Some doctors are concerned that having a mammogram soon after vaccination may cause unnecessary worry about swollen lymph nodes. For that reason, some have recommended waiting four to six weeks after your final vaccine dose before having a mammogram. That way, any lymph node swelling caused by the vaccine has time to go away.

Others, including Mayo Clinic, recommend that mammograms continue as scheduled. But be sure to tell your doctor about your vaccination, the date it occurred and which arm was affected. This information will be helpful for understanding the mammogram images.

If lymph node swelling is found on your mammogram and you've recently received the COVID-19 vaccine, the doctor who interprets your mammogram images (radiologist) will consider this when recommending whether additional imaging or follow-up is needed.

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