Safety of COVID-19 Vaccines


What You Need to Know

  • COVID-19 vaccines are safe and effective.

  • Millions of people in the United States have received COVID-19 vaccines under the most intense safety monitoring in US history.

  • CDC recommends you get a COVID-19 vaccine as soon as possible.

  • If you are fully vaccinated, you can resume many activities that you did prior to the pandemic. Learn more about what you can do when you have been fully vaccinated.

Hundreds of Millions of People Have Safely Received a COVID-19 Vaccine


More than 543 million doses of COVID-19 vaccine had been given in the United States from December 14, 2020, through February 7, 2022. To view the current total number of COVID-19 vaccinations that have been administered in the United States, please visit the CDC COVID Data Tracker.


COVID-19 vaccines are safe and effective. COVID-19 vaccines were evaluated in tens of thousands of participants in clinical trials. The vaccines met the Food and Drug Administration’s (FDA’s) rigorous scientific standards for safety, effectiveness, and manufacturing quality needed to support emergency use authorization (EUA). Learn more about EUAs in this video.external icon

The Pfizer-BioNTech, Moderna, and Johnson & Johnson/Janssen COVID-19 vaccines will continue to undergo the most intensive safety monitoring in US history. This monitoring includes using both established and new safety monitoring systems to make sure that COVID-19 vaccines are safe.


Common Side Effects After COVID-19 vaccination, some people may feel ill, with symptoms like fever or tiredness for a day or two after receiving the vaccine. These symptoms are normal and are signs that the body is building immunity. Some people have no side effects. Others have reported common side effects after COVID-19 vaccination, such as:

  • Swelling, redness, and pain at the injection site

  • Fever

  • Headache

  • Tiredness

  • Muscle pain

  • Chills

  • Nausea



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